Covid Treatment Protocols Around the World

Segment # 013

No country has had any consistent success without recognizing the need to balance the prevention of the virus with the treatment of the virus. As we have stated here before the politics of prevention driven by corrupt money and power, has interfered with the development of a cohesive treatment plan internationally. This is not to say that some countries have had great success in thwarting the high mortality rates of COVID. Ironically the much touted health systems of the west are for the most part not included in this group. And in fact as we shall see below the health systems with literally billions in resources have failed miserably. Nobody is more to blame than Anthony Fauci who’s corruption dates back to the 1980’s and his promotion of AZT to fight AIDS. Fauci blocked Hydroxychloroquine and Ivermectin to protect the Emergency Use Authorizations granted by the FDA for big Pharms vaccines. Some experts estimate conservatively the death toll from the inability to make hydroxychloroquine and ivermectin available and from the adverse reactions to the vaccines themselves are between 500,000 and 1,000,000. Anthony Fauci should be held responsible for this atrocity.

Hydroxychloroquine and Sars COV 2 - The Data

April 8, 2020 Hydroxychloroquine for SARS-CoV-2 Infection: How Did We Get Here?

David C. Helfgott, MD - https://www.infectiousdiseaseadvisor.com/home/topics/covid19/is-hydrochloroquine-the-best-treatment-optimal-choice-for-covid-19/

The randomized study by Chen et al17 was small and did not include patients with severe disease. It is notable, however, that only 4 of 62 patients progressed from nonsevere disease to severe disease, implying that the study population had quite mild illness. The other randomized study reported16 examined viral loads and did not find a difference in viral load between hydroxychloroquine-treated and untreated patients at day 7. Conversely, Gautret et al noted improved viral loads among patients in the hydroxychloroquine-treated group compared with untreated patients. However, this was a small, nonrandomized study in which the control group was culled from several hospitals with likely differing standard therapies, and 4 patients in the hydroxychloroquine group who required care in an intensive care unit or died were not included in the analysis.14 The study that evaluated azithromycin was observational in nature and few conclusions could be surmised from the set of azithromycin data.14 It should also be noted that there is concern for QTc prolongation and torsades de pointes with even short-term use of hydroxychloroquine for COVID-19.23

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

https://pubmed.ncbi.nlm.nih.gov › 16115318

Martin J Vincent 1 , Eric Bergeron, Suzanne Benjannet, Bobbie R Erickson, Pierre E Rollin, Thomas G Ksiazek, Nabil G Seidah, Stuart T Nichol

Affiliations

Abstract

Background: Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

Results: We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.

Conclusion: Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.

The Zelenko protocol ||

https://faculty.utrgv.edu/eleftherios.gkioulekas/zelenko/ZelenkoProtocol.pdf

This webpage curates content related to a treatment protocol that has been proposed by Dr.
Vladimir Zelenko for the SARS-CoV-2 virus, using hydroxychloroquine, zinc sulfate, and
azithtromycin. Dr. Zelenko has recently created his own website crowdprotocol.com to facilitate
medical research using crowd-sourced medical data from frontline primary care physicians from
all around the world. He has also co-authored and submitted his first paper for publication. See
www.thezelenkoprotocol.com for a press release. The website c19study.com is tracking research
studies of hydroxychloroquine.

Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients That Should Be Ramped Up Immediately as Key to the Pandemic Crisis

Harvey A Risch

American Journal of Epidemiology, Volume 189, Issue 11, November 2020, Pages 1218–1226, https://doi.org/10.1093/aje/kwaa093

Published:

27 May 2020

https://academic.oup.com/aje/article/189/11/1218/5847586

Abstract

More than 1.6 million Americans have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and more than 10 times that number carry antibodies to it. High-risk patients with progressing symptomatic disease currently have only hospitalization treatment, with its high mortality, available to them. An outpatient treatment that prevents hospitalization is desperately needed. Two candidate medications have been widely discussed: remdesivir and hydroxychloroquine (HCQ) + azithromycin (AZ). Remdesivir has shown mild effectiveness in hospitalized inpatients, but no trials in outpatients have been registered. HCQ + AZ has been widely misrepresented in both clinical reports and public media, and results of outpatient trials are not expected until September. Early outpatient illness is very different from later florid disease requiring hospitalization, and the treatments differ. Evidence about use of HCQ alone, or of HCQ + AZ in inpatients, is irrelevant with regard to the efficacy of HCQ + AZ in early high-risk outpatient disease. Five studies, including 2 controlled clinical trials, have demonstrated significant major outpatient treatment efficacy. HCQ + AZ has been used as the standard of care in more than 300,000 older adults with multiple comorbid conditions; the estimated proportion of such patients diagnosed with cardiac arrhythmia attributable to the medications is 47 per 100,000 users, among whom estimated mortality is less than 20% (9/100,000 users), as compared with the 10,000 Americans now dying each week. These medications need to be made widely available and promoted immediately for physicians to prescribe.

Dr. Fauci says all the ‘valid’ scientific data shows hydroxychloroquine isn’t effective in treating coronavirus

Published Wed, Jul 29 202012:31 PM EDTUpdated Fri, Jul 31 20202:39 PM EDT

Berkeley Lovelace Jr.@BerkeleyJr

Key Points

  • White House coronavirus advisor Dr. Anthony Fauci said that all the “valid” scientific data shows hydroxychloroquine isn’t effective in treating Covid-19.

  • Fauci said that the public has “got to follow the science,” adding, “if a study that’s good comes out and shows efficacy and safety for hydroxychloroquine or any other drug that we do ... you accept the scientific data.”

  • The comment by Fauci came a day after Trump said he still thinks hydroxychloroquine works against Covid-19.

Fauci Would Prescribe Chloroquine to Patient Suffering From COVID-19

https://townhall.com/columnists/larryoconnor/2020/03/25/fauci-would-prescribe-chloroquine-to-patient-suffering-from-covid19-n2565678

Larry O'Connor Posted: Mar 25, 2020 10:00 AM

Yesterday, Fauci (who, we had been recently told, was muzzled yet again) went on a bit of a media blitz. He told WMAL radio in Washington, D.C. that the president was doing a great job, that there wasn't any fundamental difference in the foundational principals in attacking the virus and that he wished the media would stop pitting him against the president.

And, on AM 990 in Philadelphia, he talked with Townhall columnist and morning host Chris Stigall about the very real hope in the hydroxychloroquine drug that has been the buzz recently.

"If you're a doctor listening to me right now and a patient with coronavirus feels like they want to try that," Stigall asked, "and you're their doctor, you're not Anthony Fauci the guy running the coronavirus task force, would you say 'alright, we'll give it a whirl'?"

"Yeah, of course, particularly if people have no other option," Fauci said. "These drugs are approved drugs for other reasons. They're anti-malaria drugs, and they're drugs against certain autoimmune diseases like lupus. Physicians throughout the country can prescribe that in an off-label way. Which means they can write it for something it was not approved for."

Pay attention to what the rich and powerful receive as treatment and get that for yourself and family. If they give HCQ to the President of the United States, its a logical bet that they believe it is the best treatment available.

IVERMECTIN

African use of Ivermectin and deaths per 100,000 November 2021

Ivermectin Trials Clinical Trials.gov prove the efficacy of Ivermectin

200 Studies either in process of competed for Ivermectin

1. Active, not recruiting

Evaluation of the Impact of the Administration of Single Dose of Ivermectin in the Early Phase of COVID-19

  • To Assess the Reduction in the Viral Load of SARS-CoV-2 in Patients Receiving Ivermectin Compared to Those Receiving Standard Care

  • Drug: Ivermectin

  • GHI Le Raincy Montfermeil
    Montfermeil, France

2. Recruiting

Ivermectin In Treatment of COVID 19 Patients

  • Covid19

  • Drug: Ivermectin

  • isolation and referal hospitals for COVID 19 patients
    Cairo, Egypt

3. Completed

SARS-CoV-2 Pre-exposure Prophylaxis With Ivermectin Retrospective Cohort Study

  • Covid19

  • Drug: Ivermectin 6 Mg Oral Tablet

  • Centro Medico Bournigal
    Puerto Plata, Dominican Republic

  • Centro Médico Punta Cana
    Punta Cana, Dominican Republic

4. Completed

Ivermectin as a Novel Therapy in COVID-19 Treatment

  • COVID

  • Drug: Ivermectin

  • Sherief Abd-Elsalam
    Tanta, Egypt

5. Completed

Has Results

Effectiveness of Ivermectin as add-on Therapy in COVID-19 Management

  • COVID 19

  • Drug: Ivermectin (IVM)

  • General Directorate of Medical City
    Bagdad, Baghdad, Iraq

6. Completed

Has Results

Sars-CoV-2/COVID-19 Ivermectin Navarra-ISGlobal Trial

  • Covid-19

  • Coronavirus Infection

  • SARS-CoV-2 Infection

  • Drug: Ivermectin

  • Drug: Placebo

  • Clinica Universidad de Navarra
    Pamplona, Navarra, Spain

7. Completed

Ivermectin Effect on SARS-CoV-2 Replication in Patients With COVID-19

  • COVID-19 Drug Treatment

  • Drug: IVERMECTIN (IVER P®) arm will receive IVM 600 µg / kg once daily plus standard care. CONTROL arm will receive standard care.

  • Hospital de Cuenca Alta
    Cañuelas, Buenos Aires, Argentina

  • Centro de Educación Médica e Investigaciones Clínicas "Norberto Quirno" CEMIC
    Buenos Aires, Ciudad De Buenos Aires, Argentina

  • Hospital de Infecciosas Francisco Javier Muñiz
    Ciudad Autonoma de Buenos Aires, Argentina

8. Completed

Has Results

Efficacy, Safety and Tolerability of Ivermectin in Subjects Infected With SARS-CoV-2 With or Without Symptoms

  • COVID-19

  • Drug: Ivermectin

  • Drug: Placebo

  • Investigacion Biomédica para el Desarrollo de Fármacos S.A. de C.V.
    Zapopan, Jalisco, Mexico

9. Recruiting New

Efficacy of Ivermectin in COVID-19

  • Safety

  • SARS-CoV2 Infection

  • Ivermectin Poisoning

  • Effect of Drug

  • Drug: Ivermectin

  • Drug: Placebo

  • Thananda Trakarnvanich
    Bangkok, Thailand

10. Not yet recruiting

The Zambia Ivermectin Trial for the Treatment and Prevention of COVID-19

  • SARS-CoV-2

  • Ivermectin

  • Drug: Ivermectin

  • Other: Prophylaxis

  • University of Zambia
    Lusaka, Zambia

11. Not yet recruiting

Remdesivir- Ivermectin Combination Therapy in Severe Covid-19

  • Covid19

  • Drug: Ivermectin

12. Completed

Has Results

Ivermectin and Human Immunity

  • Ivermectin

  • Drug: Ivermectin

  • Other: Placebo

  • University of Georgia
    Athens, Georgia, United States

13. Recruiting

Max Ivermectin- COVID 19 Study Versus Standard of Care Treatment for COVID 19 Cases. A Pilot Study

  • COVID

  • Drug: Ivermectin

  • Max Super Speciality hospital, Saket (A unit of Devki Devi Foundation)
    New Delhi, Delhi, India

14. Completed

Impact of Albendazole -Ivermectin on Wuchereria Bancrofti in Mali

  • Lymphatic Filariasis

  • Drug: ''albendazole'' and ''ivermectin''

15. Not yet recruiting

Clinical Trial to "Study the Efficacy and Therapeutic Safety of Ivermectin: (SAINTBO)

  • Covid19

  • Drug: Ivermectin

  • Drug: Placebo

  • Universidad Mayor de San Simón
    Cochabamba, Bolivia

16. Recruiting

Efficacy of Ivermectin in Outpatients With Non-severe COVID-19

  • Covid19

  • Coronavirus Infection

  • Drug: Ivermectin Tablets

  • Other: Placebo

  • Facultad de Ciencias Médicas - Universidad Nacional de Asunción
    Asunción, Paraguay

17. Completed

Physiologically-based Pharmacokinetic Modeling of Ivermectin in Healthy Human Volunteers

  • Malaria

  • Drug: Ivermectin

  • University Hospital Basel
    Basel, Switzerland

18. Completed

Effectiveness of Ivermectin and Doxycycline on COVID-19 Patients

  • Covid19

  • Drug: Ivermectin and Doxycyline

  • Drug: Standard of care

  • Akarkh Healt hdirectorate
    Baghdad, Iraq

19. Recruiting

Efficacy of Nano-Ivermectin Impregnated Masks in Prevention of Covid-19 Among Healthy Contacts and Medical Staff

  • Covid-19

  • Other: ivermectin impregnated mask

  • Zaky Aref
    Qina, Egypt

20. Terminated

COVidIVERmectin: Ivermectin for Treatment of Covid-19

  • Covid19

  • Drug: Ivermectin

  • Other: Placebo

  • IRCCS Sacro Cuore Don Calabria hospital
    Negrar, Verona, Italy

  • Policlinico S. Orsola
    Bologna, Italy

  • Ospedale Luigi Sacco
    Milan, Italy

  • (and 2 more...)

21. Not yet recruiting

Observational Study on the Use of Ivermectin as an Outpatient Treatment Option for COVID-19

  • Covid19

  • COVID-19 Pneumonia

  • COVID-19 Respiratory Infection

  • COVID-19 Acute Bronchitis

  • Drug: Ivermectin

  • Patrick Robinson MD LLC
    San Antonio, Florida, United States

22. Completed

Effectiveness of Ivermectin in SARS-CoV-2/COVID-19 Patients

  • Covid19

  • Drug: Ivermectin

  • Aijaz Zeeshan Khan Chachar
    Lahore, Punjab, Pakistan

23. Enrolling by invitation

Adverse Effects of Ivermectin Used in Egypt During COVID-19

  • Covid19

  • Ivermectin Poisoning

  • Drug Toxicity

  • Drug Side Effect

  • Drug: Ivermectin

  • Ahmed Mansour
    Shibīn Al Kawm, Menoufia, Egypt

24. Recruiting

Ivermectin Treatment Efficacy in Covid-19 High Risk Patients

  • COVID-19

  • Drug: Ivermectin 0.4mg/kg/day for 5 days

  • Sultanah Aminah Hospital
    Johor Bahru, Johor, Malaysia

  • Sultanah Bahiyah Hospital
    Alor Setar, Kadah, Malaysia

  • Sultan Abdul Halim Hospital
    Sungai Petani, Kedah, Malaysia

  • (and 9 more...)

25. Recruiting

Inhaled Ivermectin and COVID-19

  • COVID-19

  • Drug: Ivermectin Powder

  • Mansoura Faculty of Medicine
    Mansoura, Dakahlyia, Egypt

26. Completed

Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy

  • Ivermectin

  • Onchocerciasis

  • Epilepsy

  • Drug: Ivermectin

  • Centre de Recherche en Maladies Tropicales de l'Ituri
    Rethy, Ituri, Congo, The Democratic Republic of the

27. Unknown †

Topical 0.5% Ivermectin Cream for Treatment of Demodicidosis

  • Demodicidosis

  • Rosacea

  • Drug: ivermectin cream 0.5%

  • RabinMC, Dermatology dept.
    Petah-Tiqva, Israel

28. Not yet recruiting

Ivermectin Versus Standard Treatment in Mild COVID-19

  • Covid19

  • Drug: Ivermectin Tablets

  • Aliae AR Mohamed-Hussein
    Assiut, Egypt

29. Completed

Has Results

Ivermectin for Severe COVID-19 Management

  • COVID-19

  • Drug: Ivermectin

  • Afyonkarahisar Health Science University
    Afyonkarahisar, Turkey

  • Gulhane Faculty of Medicine, University of Health Sciences
    Ankara, Turkey

  • Yıldırım Beyazıt University, Ankara City Hospital
    Ankara, Turkey

  • Haydarpasa Sultan Abdulhamid Han Training and Research Hospital
    İstanbul, Turkey

30. Recruiting

The Efficacy of Ivermectin in Larger Doses in COVID-19 Treatment

  • COVID

  • Drug: Ivermectin

  • Tanta University
    Tanta, Egypt

31. Not yet recruiting

Effectiveness and Safety of Ivermectin for the Prevention of Covid-19 Infection in Colombian Health Personnel

  • Covid19

  • Healthcare Worker Patient Transmission

  • Drug: Ivermectin

  • Pontificia Universidad Javeriana
    Cali, Valle Del Cauca, Colombia

32. Completed

Ivermectin to Prevent Hospitalizations in COVID-19

  • Covid19

  • Drug: Ivermectin

  • Drug: Placebo

  • Ministry of Public Health of the Province of Corrientes
    Corrientes, Argentina

33. Completed

Ocular Changes After Ivermectin - (DOLF IVM/Oncho)

  • Onchocerciasis

  • Drug: Ivermectin 3Mg Tab

  • University of Health and Allied Sciences
    Hohoe, Ghana

34. Recruiting

Ivermectin in Treatment of COVID-19

  • COVID

  • Drug: Ivermectin

  • Waheed Shouman
    Zagazig, Sharkia, Egypt

35. Not yet recruiting

Ivermectin Safety in Small Children

  • Scabies

  • Drug: Oral ivermectin

  • Drug: Permethrin Cream

  • Other: Placebo tablet

  • Other: Placebo cream

36. Not yet recruiting

Ivermectin Nasal Spray for COVID19 Patients

  • Covid19

  • Drug: Ivermectin nasal

  • Drug: Ivermectin oral

  • Other: standard care

37. Completed

Ivermectin Reproposing for Mild Stage COVID-19 Outpatients

  • Covid19

  • SARS (Severe Acute Respiratory Syndrome)

  • Drug: Ivermectin

  • SI.PRO.SA, Ministerio de Salud Pública
    Tucumán, Argentina

38. Recruiting

Role of Ivermectin Nanosuspension as Nasal Spray in Treatment of Persistant Post covid19 Anosmia

  • Anosmia

  • Drug: ivermectin nasal spray

  • Zaky Aref
    Qina, Egypt

39. Completed

Has Results

Evaluation of the Inhibitory Effects of Topical Ivermectin on Markers of Rosacea Specific Inflammation.

  • Rosacea

  • Drug: Ivermectin

  • UCSD Division of Dermatology
    San Diego, California, United States

40. Recruiting

Efficacy of Ivermectin in COVID-19

  • COVID

  • Drug: Ivermectin 6 MG Oral Tablet (2 tablets)

  • Combined Military Hospital Lahore
    Lahore, Punjab, Pakistan

41. Completed

Has Results

Development of Ivermectin for Alcohol Use Disorders

  • Alcohol Use Disorder

  • Drug: Ivermectin

  • Drug: Placebo

  • Drug: Alcohol

  • UCLA Addictions Laboratory
    Los Angeles, California, United States

42. Completed New

Bioequivalence Study to Compare Two Tablets of Ivermectin Tablets (3 mg Ivermectin) Versus Two Tablets of Stromectol ® Tablets (3 mg Ivermectin), in Healthy Subjects Under Fasting Conditions

  • Anthelmintic Agent

  • Drug: Ivermectin tablets (3 mg Ivermectin)

  • Drug: Stromectol ® tablets

  • ACDIMA Biocenter
    Amman, Jordan

43. Completed

Has Results

USEFULNESS of Topic Ivermectin and Carrageenan to Prevent Contagion of Covid 19

  • Covid19

  • Combination Product: Iota carrageenan nasal spray and Ivermectin oral drops (used as buccal drops)

  • Hospital Eurnekian
    Buenos Aires, Argentina

44. Completed

Pharmacokinetics and Pharmacodynamics of Ivermectin in Pediatric Dengue Patients

  • Dengue Hemorrhagic Fever

  • Drug: Ivermectin

  • Faculty of Tropical Medicine Siriraj Hospital
    Bangkok Noi, Bangkok, Thailand

45. Completed

Multiple Versus Single Dose of Ivermectin for the Treatment of Strongyloidiasis

  • Strongyloidiasis

  • Drug: Ivermectin

  • Centro per le Malattie Tropicali, Ospedale Sacro Cuore
    Negrar, Verona, Italy

  • Clinica di Malattie Infettive e Tropicali
    Brescia, Italy

  • UFDID, Azienda Ospedaliero-universitaria Careggi
    Florence, Italy

  • (and 6 more...)

46. Active, not recruiting

Repeat Ivermectin Mass Drug Administrations for MALaria Control II

  • Malaria

  • Drug: Ivermectin

  • Drug: Placebo oral tablet

  • Institut de Recherche en Sciences de la Sante
    Diebougou, Sud-Ouest, Burkina Faso

47. Active, not recruiting

Rosacea and Ivermectin

  • Rosacea

  • Drug: ivermectin

  • Behavioral: digital interaction

  • Device: GPSkin

  • Wake Forest Health Sciences Dermatology
    Winston-Salem, North Carolina, United States

48. Recruiting

Treatment of Strongyloides Infection

  • Strongyloides Stercoralis Infection

  • Strongyloidiasis

  • Drug: Ivermectin

  • Jacobi Medical Center
    Bronx, New York, United States

49. Recruiting

Effect of Ivermectin Metabolites on Mosquito Survival

  • Healthy

  • Drug: Ivermectin

  • Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University
    Bangkok, Thailand

50. Completed

Has Results

Clinical Trial of Ivermectin Plus Doxycycline for the Treatment of Confirmed Covid-19 Infection

  • Covid19

  • Drug: Ivermectin and Doxycycline

  • Drug: Standard of care

  • Dhaka Medical College
    Dhaka, Bangladesh

51. Recruiting

Study in Covid-19 Patients With iveRmectin (CORVETTE-01)

  • Covid19

  • Drug: Ivermectin 3 MG

  • Drug: Placebo

  • Kitasato University
    Sagamihara, Kanagawa, Japan

52. Completed

Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy

  • Epilepsy

  • Drug: ivermectin

  • Centre de Recherche en Maladies Tropicales de l'Ituri
    Rethy, Ituri, Congo, The Democratic Republic of the

53. Completed

Ivermectin Solution Bioequivalence Study - With Food (Repeat)

  • Healthy

  • Drug: ivermectin

54. Completed

Ivermectin Solution Bioequivalence Study - Fasted

  • Healthy

  • Drug: ivermectin

  • Shandon Clinic
    Cork, Co. Cork, Ireland

55. Recruiting

Evaluation of Ivermectin Mucoadhesive Nanosuspension as Nasal Spray in Management of Early Covid-19

  • Covid19

  • Drug: intranasal ivermectin spray

  • Zaky Aref
    Qinā, Qina, Egypt

56. Completed

Ivermectin Solution Bioequivalence Study - With Food

  • Healthy

  • Drug: ivermectin

57. Not yet recruiting

Broad One Health Endectocide-based Malaria Intervention in Africa (BOHEMIA)

  • Malaria

  • Drug: Albendazole Pill

  • Drug: Ivermectin Pill

  • Drug: Ivermectin Injectable Product

58. Withdrawn

Outpatient Use of Ivermectin in COVID-19

  • Covid19

  • Drug: Ivermectin Pill

  • Drug: Placebo

  • Temple University Hospital
    Philadelphia, Pennsylvania, United States

59. Completed

Prophylaxis Covid-19 in Healthcare Agents by Intensive Treatment With Ivermectin and Iota-carrageenan

  • Covid19

  • SARS (Severe Acute Respiratory Syndrome)

  • Drug: Ivermectin / Iota-Carrageenan

  • SI.PRO.SA, Ministerio de Salud Pública
    Tucumán, Argentina

60. Completed

A Comparative Study on Ivermectin and Hydroxychloroquine on the COVID19 Patients in Bangladesh

  • Ivermectin

  • Hydroxychloroquine

  • COVID19

  • Drug: Ivermectin + Doxycycline

  • Drug: Hydroxychloroquine + Azithromycin

  • Chakoria Upazilla Health Complex
    Cox's Bazar, Bangladesh

61. Not yet recruiting

Prophylaxis of COVID-19 Disease With Ivermectin in COVID-19 Contact Persons [German: Prophylaxe Der COVID-19-Erkrankung Mit Ivermectin Bei COVID-19 Kontaktpersonen]

  • Covid19

  • Drug: Ivermectin

  • Drug: Placebo

62. Completed

Has Results

Prophylactic Ivermectin in COVID-19 Contacts

  • COVID

  • Drug: Ivermectin Tablets

  • Zagazig University
    Zagazig, Sharkia, Egypt

63. Recruiting

Randomized Phase IIA Clinical Trial to Evaluate the Efficacy of Ivermectin to Obtain Negative PCR Results in Patients With Early Phase COVID-19

  • Covid19

  • Coronavirus Infection

  • SARS-CoV Infection

  • Drug: Ivermectin

  • Drug: Placebo

  • Hospital Nacional Cayetano Heredia
    Lima, Peru

64. Not yet recruiting

The (HD)IVACOV Trial (The High-Dose IVermectin Against COVID-19 Trial)

  • Covid19

  • Drug: Ivermectin 0.6mg/kg/day

  • Drug: Ivermectin 1.0mg/kg/day

  • Drug: Placebo

  • Drug: Hydroxychloroquine

65. Recruiting

Early Treatment With Ivermectin and LosarTAN for Cancer Patients With COVID-19 Infection

  • Cancer

  • COVID

  • Coronavirus Infection

  • Drug: Placebo

  • Drug: Ivermectin

  • Drug: Losartan

  • Instituto do Cancer do Estado de Sao Paulo
    SAo Paulo, Brazil

66. Withdrawn

Bioavailability Pilot Study of Versus W0035 Versus Stromectol

  • Healthy Volunteers

  • Drug: ivermectin T1

  • Drug: ivermectin T2

  • Drug: ivermectin T3

  • Quotient Clinical
    Nottingham, United Kingdom

67. Completed

A Bioequivalence Study, Comparing Two Formulations of Ivermectin Lotion, 0.5%

  • Lice; Head Lice

  • Drug: Ivermectin Lotion, 0.5%

  • Drug: SKLICE (ivermectin) Lotion, 0.5%

  • Drug: Vehicle of the Test product

  • Taro Pharmaceuticals USA Inc.
    Hawthorne, New York, United States

68. Recruiting

Ivermectin in Adults With Severe COVID-19.

  • Covid19

  • Severe Acute Respiratory Syndrome

  • Drug: Ivermectin

  • Other: Placebo

  • Clinica CES
    Medellín, Antioquia, Colombia

69. Completed

Has Results

A Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects

  • Head Lice

  • Drug: 0.5% Ivermectin Cream

  • Drug: Placebo control

  • Arkansas Pediatric Clinic
    Little Rock, Arkansas, United States

  • Lice Cleanique, LLC
    Delray Beach, Florida, United States

  • Hill Top Research
    St Petersburg, Florida, United States

  • (and 4 more...)

70. Terminated

A Study to Compare the Efficacy and Safety of Different Doses of Ivermectin for COVID-19

  • Coronavirus Infection

  • Drug: Ivermectin

  • Other: Standard of Care

  • Hospital Univeristário da Universidade Federal de São Carlos (HU-UFSCar)
    São Carlos, São Paulo, Brazil

  • Hospital Universitário da Universidade Federal de São Carlos (HU-UFSCar)
    São Carlos, São Paulo, Brazil

71. Completed

Study Comparing Moxidectin And Ivermectin In Subjects With Onchocerca Volvulus Infection

  • Onchocerciasis

  • Drug: Moxidectin

  • Drug: Ivermectin

  • Centre de Recherche Clinique de Butembo - Université Catholique du Graben
    Butembo, Congo, The Democratic Republic of the

  • Centre de Recherche en Maladies Tropicales de l'Ituri
    Rethy, Congo, The Democratic Republic of the

  • Onchocerciasis Chemotherapy Research Center
    Hohoe, Ghana

  • Liberian Institute for Biomedical Research Clinical Research Center
    Bolahun, Lofa County, Liberia

72. Recruiting

Ivermectin vs Combined Hydroxychloroquine and Antiretroviral Drugs (ART) Among Asymptomatic COVID-19 Infection

  • Asymptomatic Infections

  • SARS-CoV2 Infection

  • Drug: Ivermectin Pill

  • Drug: Combined ART/hydroxychloroquine

  • Siriraj Hospital
    Bangkok Noi, Bangkok, Thailand

  • Siriaj Hospital
    Bangkok, N/A = Not Applicable, Thailand

  • Sireethorn Nimitvilai
    Amphoe Maueng, Nakhonpathom, Thailand

  • Golden Jubilee Medical Center
    Phutthamonthon District, Nakhonpathom, Thailand

73. Recruiting

Prophylaxis for COVID-19: Ivermectin in Close Contacts of COVID-19 Cases (IVERNEX-TUC)

  • Covid19

  • Drug: Ivermectin

  • Other: Placebo

  • SI.PRO.SA, Ministerio de Salud Pública
    Tucumán, Argentina

74. Recruiting

Comparative Study of Hydroxychloroquine and Ivermectin in COVID-19 Prophylaxis

  • Coronavirus Infections

  • Drug: Hydroxychloroquine

  • Drug: Ivermectin

  • Drug Research and Development Center (NPDM), Federal University of Ceará (UFC)
    Fortaleza, Ceará, Brazil

75. Not yet recruiting

Ivermectina Colombia (IVERCOL)

  • COVID-19 Pneumonia

  • Drug: Ivermectin

  • Drug: Placebo

76. Completed

Bioequivalence Study of Ivermectin Cream 1% in Treatment of Moderate to Severe Facial Rosacea

  • Facial Rosacea

  • Drug: Soolantra® Ivermectin cream 1%

  • Drug: Ivermectin cream 1%

  • Drug: Placebo for Ivermectin cream 1%

  • Zydus Worldwide DMCC
    Brandon, Florida, United States

  • Zydus Worldwide DMCC
    Fort Lauderdale, Florida, United States

  • Zydus Worldwide DMCC
    Miami, Florida, United States

  • (and 8 more...)

77. Completed

Ivermectin Versus Albendazole for Chronic Strongyloidiasis

  • Chronic Strongyloidiasis

  • Drug: Ivermectin

  • Drug: ivermectin

  • Drug: Albendazole

  • Siriraj Hospital
    Bangkoknoi, Bangkok, Thailand

78. Completed

Has Results

Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study

  • Malaria

  • Lymphatic Filariasis

  • Drug: Ivermectin

  • Drug: Albendazole

  • Colorado State University
    Fort Collins, Colorado, United States

  • Institut de Recherche en Sciences de la Santé
    Bobo Dioulasso, Houet, Burkina Faso

79. Complete

Has Results

Dose Ranging Study of Ivermectin Treatment Conditioner in Subjects With Head Lice Infestation

  • Pediculus Humanus Capitis (Head Lice)

  • Drug: ivermectin treatment conditioner

  • Drug: Placebo, vehicle control

  • Global Health Associates of Miami
    Miami, Florida, United States

80. Recruiting

Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted Scabies

  • Gale

  • Severe Forms of Scabies

  • Oral Parasitic Drug

  • Ivermectin

  • Drug: Ivermectin 200 µg/kg

  • Drug: Ivermectin 400 µg/kg

  • Henri Mondor Hospital
    Creteil, France

81. Not yet recruiting

Adjunctive Ivermectin Mass Drug Administration for Malaria Control

  • Malaria,Falciparum

  • Neglected Tropical Diseases

  • Strongyloidiasis

  • (and 4 more...)

  • Drug: Ivermectin

  • Drug: Placebo

  • Drug: Dihydroartemisinin-piperaquine

  • Bijagos Archipelago (islands)
    Bissau, Guinea-Bissau

82. Not yet recruiting

Ivermectin and Nitazoxanide Combination Therapy for COVID-19

  • COVID-19

  • Combination Product: Ivermectin plus Nitazoxanide

  • Other: Standard Care

83. Completed

Has Results

A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation

  • Head Lice

  • Drug: Ivermectin Cream

  • Drug: vehicle control

  • Cactus Kids Pediatrics
    Yuma, Arizona, United States

  • Universal Biopharma Research, Inc
    Dinuba, California, United States

  • Lice Source Services, Inc.
    Plantation, Florida, United States

  • (and 5 more...)

84. Completed

Efficacy and Safety of High-dose Ivermectin for Reducing Malaria Transmission: A Dose Finding Study

  • Malaria

  • Drug: ivermectin

  • Drug: placebo

  • Drug: dihydroartemisinin-piperaquine

  • Jaramogi Oginga Odinga Teaching and Referral Hospital
    Kisumu, Kenya

85. Recruiting

Ivermectin vs. Placebo for the Treatment of Patients With Mild to Moderate COVID-19

  • COVID-19

  • Drug: Ivermectin Oral Product

  • Sheba Medical Center
    Ramat-Gan, Israel

86. Completed

Ivermectin in the Treatment of Head Lice

  • Lice Infestations

  • Drug: ivermectin

  • Drug: malathion

  • Hopital Avicenne
    Bobigny, Paris, France

  • Shandon Clinic
    Cork, Co. Cork, Ireland

  • Chaim Sheba Medical Centre
    Tel Hashomer, Israel

  • Synexus Clinical Research Centre
    Reading, Berks, United Kingdom

87. Recruiting

An Outpatient Clinical Trial Using Ivermectin and Doxycycline in COVID-19 Positive Patients at High Risk to Prevent COVID-19 Related Hospitalization

  • Covid19

  • Drug: Ivermectin Tablets

  • Drug: Doxycycline Tablets

  • Drug: Placebo

  • MAX HEALTH, Subsero Health 2055 Wood Street, Suite 100
    Sarasota, Florida, United States

88. Unknown †

Efficacy and Safety of Ivermectin Against Dengue Infection

  • Dengue Fever

  • Drug: 2 days Ivermectin

  • Drug: 3 days Ivermectin

  • Drug: Placebo

  • Faculty of Medicine Siriraj Hospital, Mahidol University
    Bangkok, Thailand

89. Completed

Has Results

Clinical Endpoint Study of Ivermectin 0.5% Lotion

  • Head Lice

  • Drug: Generic Ivermectin Lotion 0.5%

  • Drug: Sklice® (Ivermectin) Lotion 0.5%

  • Drug: Vehicle Lotion

  • Site 1
    Miami, Florida, United States

90. Completed

Has Results

Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects

  • Head Lice

  • Drug: Ivermectin cream

  • Drug: vehicle control

  • Cactus Kids Pediatrics
    Yuma, Arizona, United States

  • Impact Clinical Trials
    Los Angeles, California, United States

  • Lice Cleanique, LLC
    Delray Beach, Florida, United States

  • (and 9 more...)

91. Withdrawn

Open-label Pilot Clinical Trial of Oral Ivermectin to Treat Atopic Dermatitis

  • Atopic Dermatitis

  • Drug: Ivermectin Pill

  • Stanford Hospital and Clinics
    Stanford, California, United States

92. Not yet recruiting

Safety and Efficacy of Ivermectin and Doxycycline in Treatment of Covid-19

  • Covid19

  • Drug: Ivermectin and Doxycycline

  • Other: Placebo

93. Unknown †

Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children

  • Scabies

  • Drug: Ivermectin

  • Drug: Permethrin

  • CHU de Bordeaux Hôpital Pellegrin
    Bordeaux, Aquitaine, France

  • CHG de Chalon sur Saône
    Chalon sur Saône, Bourgogne, France

  • CHU de Dijon
    Dijon, Bourgogne, France

  • (and 13 more...)

94. Completed

Ivermectin Role in Covid-19 Clinical Trial

  • Covid19

  • Drug: ivermectin

  • Drug: hydroxychloroquine

  • Drug: Placebo

  • Shebin-Elkom teaching hospital
    Shibīn Al Kawm, Menoufia, Egypt

95. Completed

Has Results

Post-treatment Effects of Ivermectin (IVM) or Diethylcarbamazine (DEC) in Loiasis

  • Loiasis

  • Drug: Diethylcarbamazine

  • Drug: Ivermectin

  • Filariasis and other Tropical Diseases Research Center
    Yaounde, Cameroon

96. Completed

Has Results

Ivermectin, Aspirin, Dexamethasone and Enoxaparin as Treatment of Covid 19

  • Severe Acute Respiratory Syndrome

  • Ventilation Pneumonitis

  • Drug: Ivermectin 5 MG/ML oral solution, Aspirin 250 mg tablets

  • Other: Ivermectin 5 mg/mL oral solution, Dexamethasone 4-mg injection, Aspirin 250 mg tablets

  • Other: Ivermectin 5 MG/ML oral solution, Dexamethasone 4-mg injection, Enoxaparin injection. Inpatient treatment with mechanical ventilation in ICU.

  • Hospital Eurnekian
    Buenos Aires, Argentina

97. Recruiting

Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas

  • Onchocerciasis

  • Drug: Moxidectin

  • Drug: Ivermectin

  • Centre de Recherche pour les Maladies Tropicales Negligees
    Rethy, Ituri, Congo, The Democratic Republic of the

98. Not yet recruiting

Efficacy, Safety and PK of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis

  • Strongyloides Stercoralis Infection

  • Drug: Moxidectin 2 mg

  • Drug: Ivermectin 3 mg

  • Drug: Placebo

  • National Centre for Parasitology, Entomology and Malaria Control
    Phnom Penh, Cambodia

99. Completed

Efficacy and Safety of Ivermectin for Treatment and Prophylaxis of COVID-19 Pandemic

  • Covid19

  • Drug: Ivermectin

  • Drug: Hydroxychloroquine

  • Behavioral: personal protective Measures

  • Benha Faculty of Medicine, Benha University
    Banhā, Qaluopia, Egypt

100. Completed

Bioequivalence Study of Ivermectin From Revemact 6 mg Tablets (Man. by EVA Pharma for Horus for Pharmaceutical Industries, Egypt) and Stromectol 2*3 mg Tablets (Merck Sharp & Dohme B.V., Haarlem, The Netherlands)

  • Healthy

  • Drug: Revemact

  • Drug: Stromectol (first dose)

  • Drug: Stromectol (second dose)

  • Genuine Research Center GRC
    Cairo, Egypt

 101. Completed

Treatment of Demodex Blepharitis With Ivermectin Gel 0.1% Plus Metronidazole 1%

  • Chronic Blepharitis

  • Drug: Ivermectin 0.1% Metronidazole 1%

  • Other: None intervention

  • Hospital de Engativa
    Bogotá, Colombia

102. Completed

Has Results

A Pharmacokinetics (PK) Study in Lice Infested Children 6 Months to 3 Years of Age

  • Head Lice

  • Drug: 0.5% Ivermectin Cream

  • Children's Investigational Research Program
    Bentonville, Arkansas, United States

  • Universal BioPharma Research, Inc
    Dinuba, California, United States

  • Impact Clinical Trials
    Los Angeles, California, United States

  • (and 2 more...)

103. Completed

Efficacy and Safety of Topical 0.5% Ivermectin Lotion for the Treatment of Head Lice Infestation in Filipinos

  • Pediculosis Capitis

  • Drug: 0.5% Ivermectin lotion

  • Drug: Vehicle

  • Clinical Trial Management and Testing Associates, Inc.
    Muntinlupa, Philippines

104. Completed

Efficacy of Ivermectin in Adult Patients With Early Stages of COVID-19 (EPIC Trial)

  • COVID-19

  • Drug: Ivermectin Oral Product

  • Drug: Placebo

  • Centro de Estudios en Infectología Pediátrica
    Cali, Valle, Colombia

105. Not yet recruiting

New Antiviral Drugs for Treatment of COVID-19

  • COVID

  • Drug Effect

  • Drug: Treatment group: will receive a combination of Nitazoxanide, Ribavirin and Ivermectin for a duration of seven days :

  • Mansoura University
    Mansoura, Select A State Or Province, Egypt

106. Completed

Has Results

CD5024 1% [Ivermectin 1%] Cream Versus Metronidazole 0.75% Cream in Papulopustular Rosacea (PPR) Study

  • Papulopustular Rosacea

  • Drug: Ivermectin 1% cream

  • Drug: Metronidazole 0.75% cream

  • Galderma Investigational Site
    Pleven, Bulgaria

  • Galderma Investigational Site
    Plovdiv, Bulgaria

  • Galderma Investigational Site
    Sofia, Bulgaria

  • (and 57 more...)

107. Completed

Eval 3-Drug Therapy Diethylcarbamize, Albendazole and Ivermectin That Could Accelerate LF Elimination Outside of Africa

  • Lymphatic Filariasis

  • Drug: Diethylcarbamazine

  • Drug: Albendazole

  • Drug: Ivermectin

  • Papua New Guinean Institute for Medical Research
    Maprik, East Sepik, Papua New Guinea

108. Recruiting

Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis

  • Onchocerciasis

  • Drug: Moxidectin

  • Drug: Ivermectin

  • Centre de Recherche pour les Maladies Tropicales Negligees
    Rethy, Ituri, Congo, The Democratic Republic of the

109. Completed

Hydroxychloroquine and Ivermectin for the Treatment of COVID-19 Infection

  • COVID-19

  • Drug: Hydroxychloroquine

  • Drug: Ivermectin

  • Drug: Placebo

  • Jose Manuel Arreola Guerra
    Aguascalientes, Mexico

110. Completed

Efficacy and Safety of Ivermectin and Doxycycline in Combination or IVE Alone in Patients With COVID-19 Infection.

  • COVID-19 Patients

  • Drug: Ivermectin + Doxycycline + Placebo

  • Drug: Ivermectin + Placebo

  • Drug: Placebo

  • Icddr,B
    Dhaka, Bangladesh

111. Recruiting

Efficacy of Subcutaneous Ivermectin With or Without Zinc in COVID-19 Patients

  • Coronavirus Infection

  • COVID

  • Sars-CoV2

  • Drug: Ivermectin Injectable Solution

  • Other: Injectable Placebo

  • Drug: Zinc

  • (and 2 more...)

  • Ali Clinic
    Lahore, MA, Pakistan

  • Shaikh Zayed Hospital
    Lahore, Punjab, Pakistan

112. Completed

Has Results

Azithromycin - Ivermectin Mass Drug Administration for Skin Disease

  • Scabies

  • Yaws

  • Impetigo

  • Drug: Ivermectin

  • Drug: Azithromycin

  • Drug: Permethrin

  • Atoifi Adventist Hospital
    Atoifi, Malaita, Solomon Islands

113. Completed

Has Results

Albendazole Plus High Dose Ivermectin for Trichuriasis in Pediatric Patients

  • Trichuris Infection

  • Helminthiasis

  • Drug: Ivermectin

  • Drug: Albendazole

  • IIET
    Oran, Salta, Argentina

  • Universidad Autónoma de Honduras
    Tegucigalpa, Honduras

114. Completed

Pharmacokinetics & Pharmacodynamics of Diethylcarbamazine (DEC)+ Albendazole (ALB) + Ivermectin (IVE)

  • Wuchereria Bancrofti Infection

  • Drug: Ivermectin, Diethylcarbamazine Albendazole (IDA)

  • Agboville District Hospital
    Agbobille, Côte D'Ivoire

115. Completed

Efficacy and Safety of IVM/ALB Co-administration

  • Trichuriasis

  • Drug: Albendazole

  • Drug: Albendazole and Ivermectin

  • Centre Suisse de Recherches Scientifiques en Côte d'Ivoire (CSRS)
    Abidjan, Côte D'Ivoire

  • Lao Tropical and Public Health Institute
    Sisattanak, Lao People's Democratic Republic

  • Public Health Laboratory Ivo de Carneri, P.O. Box 122
    Chake Chake, Pemba, Tanzania

116. Enrolling by invitation

Moxidectin for LF, Cote d'Ivoire (DOLF)

  • Lymphatic Filariasis

  • Drug: Ivermectin

  • Drug: Diethylcarbamazine

  • Drug: Albendazole

  • Drug: Moxidectin

  • Regional Hospital of Agboville, Southern Cote d'Ivoire
    Agboville, Côte D'Ivoire

117. Completed

Has Results

Clinical Endpoint Study of Ivermectin 1% Cream

  • Moderate to Severe Papulopustular Rosacea

  • Drug: Ivermectin Cream, 1%

  • Drug: Placebo/Vehicle cream

  • Investigator site 1
    Arlington Heights, Illinois, United States

118. Terminated

Has Results

Efficacy of Higher Albendazole and Ivermectin Doses on Wuchereria Bancrofti Microfilarial Clearance in Malawi

  • Lymphatic Filariasis

  • Drug: Albendazole 400mg and ivermectin 200mcg/kg

  • Drug: Albendazole and ivermectin

  • Drug: albendazole 800mg and ivermectin 400mcg/kg bi-annually

  • Karonga Prevention Study
    Karonga, Malawi

119. Active, not recruiting

Efficacy and Safety of MOX/ALB Co-administration

  • Trichuriasis

  • Ascariasis

  • Hookworm Infections

  • Drug: Moxidectin 2 mg Oral Tablet

  • Drug: Albendazole 400 mg Oral Tablet

  • Drug: Ivermectin 3 mg Oral Tablet

  • Centre Suisse de Recherches Scientifiques en Côte d'Ivoire (CSRS)
    Abidjan, Côte D'Ivoire

120. Recruiting

Ivermectin-Azithromycin-Cholecalciferol (IvAzCol) Combination Therapy for COVID-19

  • COVID

  • Drug: Ivermectin

  • Drug: Azithromycin

  • Drug: Cholecalciferol

  • Outpatient treatment
    Mexico City, Mexico

121. Not yet recruiting

Cluster RCT of Co-administration Azithromycin, Albendazole & Ivermectin

  • Trachoma

  • Lymphatic Filariases

  • Drug: Administration of Albendazole on Day 1

  • Drug: Administration of Ivermectin on Day 1

  • Drug: Administration of Azithromycin on Day 1

  • Drug: Administration of Azithromycin on Day 15

122. Completed

Trial of Artemether-Lumefantrine Alone and in Combination With Ivermectin to Reduce Post-Treatment Malaria Transmission

  • Malaria

  • Drug: Artemether-lumefantrine combination

  • Drug: Artemether-lumefantrine combination + single dose Ivermectin

  • Drug: Artemether-lumefantrine combination + repeated dose Ivermectin

  • Centre National de Recherche et de Formation sur le Paludisme
    Ouagadougou, Burkina Faso

123. Completed

Treatment of Pediculosis (Head Lice) in Senegal

  • Pediculoses

  • Drug: Ivermectin Oral Product

  • Institut de Recherche pour le Developpement
    Dakar, Senegal

124. Completed

Twice Yearly Treatment for the Control of LF

  • Lymphatic Filariasis

  • Helminth Infection

  • Drug: 400 μg/kg Ivermectin + 400 mg Albendazole

  • Noguchi Memorial Institute for Medical Research
    Legon-Accra, Ghana

125. Completed

Has Results

A Clinical Endpoint Bioequivalence Study to Assess Efficacy and Safety of Ivermectin 0.5% Lotion in the Treatment of Head Lice

  • Head Lice

  • Drug: Ivermectin 0.5% Topical Application Lotion

  • Drug: Ivermectin 0.5% Topical Application Lotion [SKLICE]

  • Drug: Placebo 0% Lotion

  • Site 105
    Dinuba, California, United States

  • Site 104
    Miami, Florida, United States

  • Site 101
    Plantation, Florida, United States

  • (and 3 more...)

126. Completed

Ivermectin Neurotoxicity and ABCB1 Gene Mutations

  • DNA Sequencing

  • Uh Montpellier
    Montpellier, France

127. Withdrawn

Clinical Trial Evaluating the Safety and Efficacy of Moxidectin 2 mg Ivermectin-controlled in Loa Loa Microfilaremic Patients

  • Onchocerciasis, Ocular

  • Loiasis

  • Drug: Moxidectin 2 MG Oral Tablet

  • Drug: Ivermectin 3Mg Tab

  • Drug: Placebo oral tablet

  • Centre de recherche sur les filarioses et autres maladies tropicales (CRFilMT)
    Yaoundé, Cameroon

128. Completed

Has Results

Oracea Soolantra Association in Participants With Severe Rosacea

  • Rosacea

  • Drug: Ivermectin 1% cream

  • Drug: Doxycycline 40 mg MR (30 mg Immediate Release & 10 mg Delayed Release beads) capsules

  • Other: Oral placebo capsules

  • Private Practice
    Fort Smith, Arkansas, United States

  • Private practice
    Sacramento, California, United States

  • Private practice
    Boca Raton, Florida, United States

  • (and 18 more...)

129. Active, not recruiting

Mass Drug Administration of Ivermectin and Dihydroartemisinin-piperaquine as an Additional Intervention for Malaria Elimination

  • Malaria

  • Drug: dihydroartemisinin-piperaquine (DP)

  • Drug: ivermectin (IVM)

  • Other: standard malaria control interventions only

  • Basse Villages
    Basse Santa Su, Gambia

130. Withdrawn

Safety Study of Combined Azithromycin, Ivermectin and Albendazole for Trachoma and Lymphatic Filariasis

  • Trachoma

  • Lymphatic Filariasis

  • Drug: azithromycin

  • Drug: ivermectin

  • Drug: albendazole

  • Drug: placebo

  • National Institute of Health, Ministry of Health
    Maputo, Mozambique

131. Not yet recruiting

Efficacy and Safety of MOX/ALB vs. IVM/ALB Co-administration

  • Trichuriasis

  • Ascariasis

  • Hookworm Infections

  • Helminthes; Infestation, Intestinal

  • Drug: moxidectin (8 mg) / albendazole (400 mg)

  • Drug: ivermectin (200 µg/kg) / albendazole (400 mg)

  • Drug: ALBENDAZOLE 400 Mg ORAL TABLET [ZENTEL]

  • (and 2 more...)

132. Completed

Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji

  • Lymphatic Filariases

  • Scabies

  • Impetigo

  • Soil Transmitted Helminths

  • Drug: 3 drug dose - IDA

  • Drug: 3 drug dose - IDA with second dose of ivermectin

  • Drug: 2 drug dose - DA

  • Ministry of Health and Medical Services
    Suva, Fiji

133. Completed

PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs )

  • Lymphatic Filariasis

  • Yaws

  • Trauma

  • Drug: Azithromycin

  • Drug: Albendazole

  • Drug: Ivermectin

  • Drug: Diethylcarbamazine

  • Lihir Medical Centre
    Londolovit, New Ireland Province, Papua New Guinea

134. Completed

Comparison of the Efficacy and Safety of Ivermectin to Permethrin

  • Scabies

  • Drug: Administration of ivermectin or permethrin

  • University Hospital Ghent
    Ghent, Belgium

135. Enrolling by invitation

Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis

  • Strongyloides Stercoralis Infection

  • Drug: Moxidectin

  • Drug: Ivermectin

  • Drug: Placebo oral tablet

  • National Centre for Parasitology, Entomology and Malaria Control
    Phnom Penh, Cambodia

  • National Institute of Public Health
    Vientiane, Lao People's Democratic Republic

136. Not yet recruiting

Safety & Efficacy of Low Dose Aspirin / Ivermectin Combination Therapy for Treatment of Covid-19 Patients

  • Covid19

  • Drug: 3-dayIVM 200 mcg/kg/day/14-day 75mgASA/day + standard of care (intervention 1)

137. Completed

Veron Scabies Education and Eradication Program

  • Scabies

  • Drug: Ivermectin

  • Drug: Permethrin 5% lotion

  • Barrio Nuevo
    Veron, La Altagracia, Dominican Republic

138. Completed

Effectiveness of Combined Albendazole and Ivermectin Treatment for Intestinal Worm Infections

  • Ascariasis

  • Trichuriasis

  • Hookworm Infection

  • (and 2 more...)

  • Drug: albendazole vs. combined albendazole/ivermectin treatment

  • Various elementary schools
    Poptun, Peten, Guatemala

139. Completed

Has Results

MirvasO Soolantra Association In the Treatment of Moderate to Severe rosaCea.

  • Rosacea

  • Drug: Brimonidine 0.33% gel (Br)

  • Other: CD07805/47 (Br) placebo gel

  • Drug: Ivermectin 1% cream (IVM)

  • Other: CD5024 (IVM) placebo cream

  • Fort Smith, Arkansas, United States

  • Rogers, Arkansas, United States

  • Sacramento, California, United States

  • (and 10 more...)

140. Completed

Has Results

Evaluation of Prognostic Modification in COVID-19 Patients in Early Intervention Treatment

  • Covid19

  • Drug: Azithromycin / Ivermectin / Ribaroxaban / Paracetamol

  • Drug: Azithromycin / Ribaroxaban / Paracetamol

  • Alma Italia Guerrero Martinez
    Mexico, Distrito Federal, Mexico

141. Recruiting

MANS-NRIZ Trial for COVID-19 Treatment : Extension Study

  • COVID-19 Pneumonia

  • Drug: Ivermectin,ribavirin ,nitazoxanide and zinc

  • Mansoura University Hospital
    Mansoura, Select A State Or Province, Egypt

142. Completed

Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)

  • Lymphatic Filariasis

  • Onchocerciasis

  • Soil Transmitted Helminth (STH) Infections

  • Drug: Annual versus Semiannual Albendazole plus Ivermectin MDA

  • Ivory Coast National Program Against Schistosomiasis, Geohelminths and Filariasis
    Abidjan, Lagune-Cocody, Côte D'Ivoire

143. Completed

IVM Alone vs ALB + IVM Against Onchocerciasis

  • Onchocerciasis

  • Drug: Ivermectin

  • Drug: Albendazole

  • Committee on Human Research Publications and Ethics
    Kumasi, Ashanti, Ghana

144. Enrolling by invitation

Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia

  • Lymphatic Filariasis

  • Onchocerciasis

  • Soil Transmitted Helminth (STH) Infections

  • Drug: Annual versus Semiannual Albendazole plus Ivermectin Mass Drug Administration

  • Liberian Institute of Biomedical Research
    Charlesville, Margibi, Liberia

145. Unknown †

Management of Soil-transmitted Helminthiasis and Strongyloidiasis

  • Helminthiasis

  • Strongyloides Stercoralis Infection

  • Drug: Ivermectin + Albendazole

  • Instituto de Investigación en Enfermedades Tropicales, Universidad Nacional de Salta
    Orán, Salta, Argentina

146. Recruiting

Repurposed Approved and Under Development Therapies for Patients With Early-Onset COVID-19 and Mild Symptoms

  • Covid19

  • SARS-Associated Coronavirus

  • Drug: Fluvoxamine Maleate 100 MG [Luvox]

  • Drug: Doxazosin 2 Mg Oral Tablet

  • Drug: Ivermectin 06 mg Oral Tablet

  • (and 3 more...)

  • City of Betim
    Betim, MG, Brazil

  • Hospital e Maternidade Santa Rita
    Contagem, MG, Brazil

  • City of Governador Valadares
    Governador Valadares, MG, Brazil

  • (and 8 more...)

147. Completed

Efficacy of Ivermectin and Albendazole Against Onchocerciasis in the Volta Region, Ghana

  • Onchocerciasis

  • Drug: IVM plus ALB

  • Drug: IVM

  • Onchocerciasis Chemotherapy Research Centre, (OCRC) Municipal Hospital
    Hohoe, Ghana

148. Completed

Bioavailability and Safety of Two Oral Fixed Dose Preparations Containing 18 mg Ivermectin (IVM 18 MG TABLETS, LICONSA S.A., Spain) Versus Reference Dosing (Weight Based) Containing 6 mg Ivermectin (REVECTINA®, Abbott Laboratórios do Brasil Ltda, Brazil)

  • Helminthiasis

  • Drug: T1, T2, T3

  • Drug: T1,T3,T2

  • Drug: T2,T1,T3

  • (and 3 more...)

149. Completed

Safety of Co-administration of IDA and Azithromycin for NTDs ( ComboNTDs )

  • Trachoma

  • Yaws

  • Lymphatic Filariases

  • (and 2 more...)

  • Drug: Albendazole on Day 1

  • Drug: Ivermectin on Day 1

  • Drug: Diethylcarbamazine on day 1

  • (and 2 more...)

  • Namatanai Hospital
    Namatanai, Papua New Guinea

150. Completed

Safety of the Co-administration of Three Drugs for Trachoma and Lymphatic Filariasis Elimination

  • Parasitic Diseases

  • Bacterial Diseases

  • Drug: triple co administration at once of the combination of Albendazole + ivermectin + azithromycin

  • Centre National D'Appui a la lutte contre la Maladie
    Bamako, Mali

151. Completed

Study Evaluating Orally Administered Moxidectin In Subjects With Onchocerca Volvulus Infection

  • Onchocerciasis

  • Drug: 2 mg moxidectin

  • Drug: ivermectin 150 mcg/kg

  • Drug: 4 mg moxidectin

  • Drug: 8 mg moxidectin

  • Onchocerciasis Chemotherapy Research Center
    Hohoe, Volta Region, Ghana

152. Completed

Pharmacokinetic and Mosquito-Lethal Effects of Ivermectin (IVM), Primaquine (PQ), Dihydroartemisinin-Piperaquine (DHA-PQP) and Albendazole (ABZ) in Healthy Subjects

  • Drug Combination

  • Pharmacokinetics

  • Healthy

  • Drug: IVM, IVM and PQ, IVM and DHA-PQP, IVM and DHA-PQP and PQ

  • Drug: PQ and DHA-PQP and PQ

  • Drug: DHA-PQP

  • Faculty of Tropical Medicine
    Bangkok, Thailand

153. Completed

Safety and Efficacy of Drug Combinations Against Triple Infections

  • Parasitic Diseases

  • Drug: albendazole + ivermectin + praziquantel

  • Drug: albendazole + ivermectin + (1 week later) praziquantel

  • Vector Control Division
    Kampala, Uganda

154. Completed

Effect of Albendazole Dose on Clearance of Filarial Worms

  • Lymphatic Filariasis

  • Drug: Albendazole

  • Drug: Ivermectin

  • University of Bamako, Faculty of Medicine, Pharmacy and Odontostomatology
    Bamako, Mali

155. Completed New

Loiasis Cross-reactive Antigenemia and Treatment-related Adverse Events

  • Loiasis

  • Drug: Ivermectin

  • Centre de Recherche sur les Filarioses et autres Maladies Tropicales (CRFilMT)
    Yaoundé, Cameroon

156. Completed

Death to Onchocerciasis and Lymphatic Filariasis (DOLF) Triple Drug Therapy for Lymphatic Filariasis

  • Lymphatic Filariasis

  • Drug: 3 drug dose - IDA

  • Drug: 2 drug dose - DA

  • Ministere de la Sante Publique et de la Population
    Port-au-Prince, Haiti

  • Vector Control Research Centre
    Puducherry, India

  • Universitas Indonesia
    Jakarta, Indonesia

  • Papua New Guinea Institute for Medical Research
    Madang, Papua New Guinea

157. Completed

Lymphatic Filariasis (LF) in Ivory Coast

  • Lymphatic Filariasis

  • Drug: Albendazole

  • Drug: Ivermectin

  • Drug: Diethylcarbamazine

158. Terminated

Can Presumptive Anthelminthic Treatment Delay the Progression of HIV in ART-naïve Patients in Rural Africa?

  • HIV Infections

  • Helminthiasis

  • Drug: Praziquantel, Ivermectin, Albendazole

  • Chronic Disease Clinic of St. Francis Designated District Hospital
    Ifakara, Kilombero, Tanzania

159. Unknown †

Insecticide Resistance Management in Burkina Faso and Côte d'Ivoire

  • Malaria

  • Device: Insecticidal paint

  • Device: Larvicide

  • Biological: Ivermectin

  • Behavioral: IEC

160. Recruiting

Comparative Therapeutic Efficacy and Safety of Different Antiviral and Anti Inflammatory Drugs in COVID-19 Patients.

  • Covid19

  • Pneumonia

  • Drug: Remdesivir

  • Drug: Hydroxychloroquine

  • Drug: Tocilizumab

  • (and 2 more...)

  • Beni-suef University
    Banī Suwayf, Egypt

161. Recruiting

COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

  • Covid19

  • SARS-CoV Infection

  • Drug: Metformin

  • Drug: Placebo

  • Drug: Fluvoxamine

  • Drug: Ivermectin

  • Olive View UCLA Medical Center
    Sylmar, California, United States

  • Anschutz Health and Wellness Center
    Aurora, Colorado, United States

  • New West Physicians
    Golden, Colorado, United States

  • (and 4 more...)

162. Recruiting

Novel Agents for Treatment of High-risk COVID-19 Positive Patients

  • COVID

  • Sars-CoV2

  • Drug: Ivermectin

  • Drug: Camostat Mesilate

  • Dietary Supplement: Artemesia annua

  • Drug: Artesunate

  • University of Kentucky Markey Cancer Center
    Lexington, Kentucky, United States

163. Not yet recruiting

A Phase III Confirmatory Study of K-237

  • Covid19

  • Drug: K-237 0.3-0.4mg/kg (once daily)

  • Drug: Placebo 0.3-0.4mg/kg (once daily)

164. Recruiting

Analysis of the Microbiome in Rosacea

  • Rosacea

  • Drug: Doxycycline

  • Drug: Ivermectin Topical

  • Cutaneous Translational Research Program, Department of Dermatology
    Baltimore, Maryland, United States

165. Completed

A Preventive Treatment for Migrant Workers at High-risk of COVID-19

  • Covid-19

  • Drug: Hydroxychloroquine Sulfate Tablets

  • Drug: Ivermectin 3mg Tab

  • Drug: Zinc

  • (and 2 more...)

  • Tuas South Dormitory
    Singapore, Singapore

166. Completed

Has Results

Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands

  • Scabies

  • Head Lice

  • Drug: Ivermectin

  • Drug: Permethrin 5%

  • Drug: Malathion Shampoo 0.5%

  • Atoifi Adventist Hospital
    Atoifi, Malaita, Solomon Islands

167. Enrolling by invitation

Safety and Efficacy of IDA for Onchocerciasis

  • Onchocerciasis

  • Drug: IVM w/ ALB

  • Drug: Single dose of IDA

  • Drug: Three daily doses of IDA

  • University of Health and Allied Sciences
    Hohoe, Ghana

168. Enrolling by invitation

Tuberculosis - Learning the Impact of Nutrition

  • Tuberculosis

  • Malnutrition

  • Helminth Infection

  • Dietary Supplement: Nutritional Supplementation Meal

  • Dietary Supplement: Multivitamin

  • Drug: Anti-parasitic medications

  • Jawaharlal Institute of Postgraduate Medical Education and Research
    Pondicherry, Tamil Nadu, India

169. Completed

Epidemiology and Control of Mansonella Perstans Infection in Uganda

  • Mansonelliasis

  • Pruritus

  • Lymphoedema

  • Abdominal Pains

  • Drug: ivermectin and albendazole

  • Luwero
    Luwero and Mukono, Luwero and Mukono Districts, Uganda

170. Recruiting

ACTIV-6: COVID-19 Study of Repurposed Medications

  • Covid19

  • Drug: Ivermectin

  • Drug: Fluvoxamine

  • Drug: Fluticasone

  • Other: Placebo

  • Emory Healthcare
    Atlanta, Georgia, United States

  • NorthShore Medical Group
    Evanston, Illinois, United States

  • Duke Clinical Research Institute
    Durham, North Carolina, United States

  • (and 5 more...)

171. Completed

Safety and Efficacy of Drug Combinations Against Trichuris Trichiura

  • Parasitic Diseases

  • Drug: albendazole

  • Drug: mebendazole

  • Drug: ivermectin

  • (and 2 more...)

  • Vector Control Division
    Kampala, Uganda

172. Recruiting

Prevention and Treatment for COVID -19 (Severe Acute Respiratory Syndrome Coronavirus 2 SARS-CoV-2) Associated Severe Pneumonia in the Gambia

  • Covid-19

  • Drug: Ivermectin

  • Drug: ASP

  • Drug: Placebo

  • Mrcg@Lshtm
    Fajara, Gambia

173. Completed

Exploratory Ph I Trial of the Active IMP in Healthy Volunteers in Relation to COVID-19

  • Covid19

  • Drug: Ivermectin

  • Drug: Placebo

  • MAC Clinical Research Manchester (Early Phase Unit), Neuroscience Centre of Excellence
    Manchester, Greater Mancherster, United Kingdom

174. Recruiting

Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection

  • Onchocerciasis

  • Drug: ABBV-4083

  • Drug: Placebo for ABBV-4083

  • Drug: Albendazole

  • (and 3 more...)

  • Hôpital Général de Référence de Kimpese
    Kimpese, Kongo Central, Congo, The Democratic Republic of the

  • Hôpital Général de Référence de Masi-Manimba
    Masi-Manimba, Kwilu, Congo, The Democratic Republic of the

175. Completed

Has Results

Comparative Safety and Efficacy of Two Treatments in the Treatment of Inflammatory Lesions of Rosacea

  • Rosacea

  • Drug: Ivermectin

  • Drug: Ivermectin (reference)

  • Drug: Placebo

176. Completed

Montelukast - a Treatment Choice for COVID-19

  • Covid19

  • SARS-CoV-2 Infection

  • Drug: Montelukast

  • Drug: Hydroxychloroquine

  • Drug: Ivermectin

  • Department of Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China
    Shanghai, China

  • Shaukat Khanum Memorial Cancer Hospital & Research Centre, Johar Town, Lahore, Pakistan
    Lahore, Punjab, Pakistan

177. Active, not recruiting

Trial of Combination Therapy to Treat COVID-19 Infection

  • COVID

  • Covid-19

  • Corona Virus Infection

  • (and 4 more...)

  • Drug: Ivermectin

  • Drug: Doxycycline Hcl

  • Dietary Supplement: Zinc

  • (and 2 more...)

  • ProgenaBiome
    Ventura, California, United States

178. Recruiting

Escalated Therapy of Scabies With INFECTOSCAB 5% (Permethrin)

  • Scabies

  • Drug: InfectoScab 5 % Creme

  • Drug: Permethrin 10 % Creme

  • Drug: Driponin 3 mg Tabletten

  • Uniklinik RWTH Aachen
    Aachen, Germany

  • Universitätsklinikum Augsburg
    Augsburg, Germany

  • Klinikum Darmstadt
    Darmstadt, Germany

  • (and 5 more...)

179. Recruiting

Risk Stratification of COVID-19 Using Urine Biomarkers

  • Covid19

  • Urine

  • Biomarker

  • Acute Respiratory Failure With Hypoxia

  • MD Mount Sinai
    Baltimore, Maryland, United States

  • Hospital das Clinicas Ribeirao Preto
    Ribeirão Preto, San Paulo, Brazil

  • Danish National Biobank
    København, Denmark

  • (and 4 more...)

180. Recruiting

Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)

  • COVID-19

  • Drug: Favipiravir

  • Drug: Monoclonal antibodies

  • Drug: Ivermectin

  • (and 2 more...)

  • Faculty of Tropical Medicine, Mahidol University
    Bangkok, Thailand

181. Completed

Prevalence Studies After Triple Drug Therapy for Lymphatic Filariasis

  • Lymphatic Filariases

  • Drug: 2 drug dose - DA

  • Drug: 3 drug dose - IDA

  • Ministry of Health and Medical Services
    Suva, Fiji

  • Ministere de la Sante Publique et de la Population
    Port-au-Prince, Haiti

  • Vector Control Research Centre
    Puducherry, India

  • (and 2 more...)

182. Recruiting

Novel Regimens in COVID-19 Treatment

  • COVID

  • Corona Virus Infection

  • Drug: Nitazoxanide

  • Tanta University, Assiut University
    Tanta, Egypt

  • Sherief Abd-Elsalam
    Tanta, Egypt

183. Completed

Doxycycline to Treat Mansonella Perstans Infection in Patients With and Without Lymphatic Filariasis

  • Mansonella Perstans Infection

  • Mp Microfilaremia

  • Drug: Doxycycline

  • National Institute of Allergy and Infectious Diseases (NIAID), 9000 Rockville Pi
    Bethesda, Maryland, United States

184. Not yet recruiting

Worldwide Trends on COVID-19 Research After the Declaration of COVID-19 Pandemic

  • COVID-19

  • Drug: Convalescent Plasma Transfusion

  • Drug: Hydroxychloroquine

  • Drug: DAS181

  • (and 2 more...)

185. Terminated

Effectiveness of Permethrin Impregnated Underwear in Preventing Louse Proliferation in Infected Homeless

  • Body's Louses

  • Drug: Permethrin impregnated

  • Drug: no Permethrin impregnated

  • Assistance Publique Hopitaux de Marseille
    Marseille, France

186. Not yet recruiting

Evaluation of Strongyloidiasis in Ecuador: a fieLd Laboratory Accuracy Study

  • Strongyloidiasis

  • Strongyloides Stercoralis Infection

  • Diagnostic Test: Different diagnostic tests

  • Centro de Epidemiologia Comunitaria y Medicina Tropical (CECOMET)
    Esmeraldas, Ecuador

187. Recruiting

Field Studies on the Feasibility of Interrupting the Transmission of Soil-transmitted Helminths (STH)

  • Helminthiasis

  • Filariasis

  • Drug: Albendazole

  • Institut de Recherche pour le Développement
    Comé, Benin

  • Christian Medical College
    Vellore, India

  • London School of Hygiene and Tropical Medicine
    Mangochi, Malawi

188. Unknown †

Treatment of Nodding Syndrome - A Randomized Blinded Placebo-Controlled Crossover Trial of Oral Pyridoxine and Conventional Anti-Epileptic Therapy, in Northern Uganda - 2012

  • Nodding Syndrome

  • Drug: Pyridoxine

  • Drug: Sodium Valproate

  • Drug: Phenytoin

  • Drug: Placebo

  • Kitgum Nodding Syndrome Treatment Center, Kitgum General Hospital
    Kitgum, Uganda

189. Completed

Prevalence of LF Infection in Districts Not Included in LF Control Activities

  • Lymphatic Filariases

  • Onchocerciasis

  • Diagnostic Test: Diagnosis of lymphatic filariasis

  • Diagnostic Test: Diagnosis of lymphatic Filariasis and onchocerciasis

  • Diagnostic Test: DEC Patch

  • Villages in Eastern and Volta Region
    Eastern And Volta Regions, Ghana

190. Completed

Study of Patients With Strongyloides Stercoralis Infection

  • HIV Infection

  • Nematode Infection

  • Strongyloidiasis

  • National Institutes of Health Clinical Center, 9000 Rockville Pike
    Bethesda, Maryland, United States

191. Recruiting

East New Britain Province Monitoring & Evaluation

  • Lymphatic Filariasis Elimination by Mass Drug Administration

  • Monitoring and Evaluation of Mass Drug Administration for Lymphatic Filariasis

  • Acceptability of Mass Drug Administration for Lymphatic Filariasis

  • Other: Observational

  • East New Britain Provincial Health Authority
    Kokopo, East New Britain Province, Papua New Guinea

192. Recruiting

Host Response to Infection and Treatment in Filarial Diseases

  • Filariasis

  • Helminthiasis

  • Parasitic Infection

  • (and 2 more...)

  • National Institutes of Health Clinical Center, 9000 Rockville Pike
    Bethesda, Maryland, United States

193. Completed

The Sero-Prevalence and Genetic Study for the Infectious Diseases and Metabolic Syndrome in Solomon Islands

  • Flavivirus Infection

  • Alphavirus Infections

  • Malaria

  • (and 4 more...)

  • Other: diagnosis, treatment and education

  • Kaoshing Medical University Chung-Ho Memorial Hospital
    Kaoshiung, Taiwan

194. Unknown †

Clinical Features and Potential Etiology of Epilepsy and Nodding Syndrome in the Mahenge Area, Ulanga District

  • Nodding Syndrome

  • Epilepsy

  • Onchocerciasis

  • Cognitive Impairment

  • Other: no intervention

  • Mahenge Epilepsy Clinic
    Mahenge, Tanzania

195. Recruiting

Safety, Tolerability, and Pharmacokinetics of EQU-001 in Healthy Volunteers

  • Safety Issues

  • Drug: EQU-001

  • Drug: Placebo

  • Clinical Pharmacology of Miami
    Hialeah, Florida, United States

196. Completed

Pulmonary Nodule Detection: Comparison of an Ultra Low Dose vs Standard Scan.

  • Lung Cancer

  • Smoking

  • Radiation Exposure

  • Device: Ultra low dose chest CT

  • Device: Low dose chest CT

  • University Hospital Grenoble
    Grenoble, France

197. Completed

Effect of the Number of Needle Revolutions Inside the Node on the Diagnostic Yield of EBUS-TBNA in Sarcoidosis

  • Sarcoidosis

  • Procedure: 10 revolutions

  • Procedure: 20 revolutions

  • Post Graduate Institute of Medical Education and Research
    Chandigarh, UT, India

198. Completed

The Effect and Mechanism of Bronchoscopic Lung Volume Reduction by Endobronchial Valve in Korean Emphysema Patients

  • Pulmonary Emphysema

  • Device: Endobronchial valve

  • Department of Pulmonary and Critical Care Medicine and Clinical Research Center for Chronic Obstructive Airway Diseases, Asan Medical Center, University of Ulsan College of Medicine
    Seoul, Korea, Republic of

199. Recruiting

Clinical Evaluation of a New Form of Cancer Therapy Based on the Principles of Atavistic Metamorphosis (Atavistic Chemotherapy).

  • Neoplasms

  • Drug: Anti-Bacterial Agents

  • Drug: Anti-Fungal Agents

  • Drug: Anti-Protozoal Agents

  • Dr. Frank Arguello Cancer Clinic
    San Jose del Cabo, Baja California Sur, Mexico

  • Instituto de Ciencia y Medicina Genomica
    Torreon, Coahuila, Mexico

200. Completed

Host Response to Infection and Treatment in Lymphatic Filarial Disease in India

  • Lymphatic Filarial Disease

  • Tuberculosis Research Centre
    Chennai, India

 In my judgment we have made the case for ivermectin based on science. The data is there and when you compare the counter argument from the government and big Pharm it is at best vacuous failing to admit both the documented success and safety of this drug.  I may have failed to substantially document the motives that we must attribute to the US Government, the Talking heads, and big Pharm. Look to Mexico and India and the data cited below on what happened after ivermectin was introduced  to COVID positive patients. The medical community knows this, big Pharm knows this, the government knows this… CNN and MSNBC probably don’t,  given their limited affinity for journalism. Point being.. trashing ivermectin is purposeful and we must all do our own research to make our medical decisions….  regardless of our political persuasion COVID pretty much attacks without checking. And think about this if the case for ivermectin was baseless  would the argument against be censorship or a robust scientific debate. If you can’t win the argument, you , limit the facts to the public, discredit the opposing experts, and scare the crap out of everybody. Sound familiar? We live in scary times.

After Mexico City introduced ivermectin plan, COVID hospitalizations and deaths disappeared

An initiative in Mexico City to prescribe ivermectin to COVID-19 positive patients has resulted in a 52–76 percent reduction in hospitalizations.

IvermectinShutterstock

 

Wed May 26, 2021 - 5:10 pm EDT

MEXICO CITY, May 26, 2021 (LifeSiteNews) — A city-wide initiative in Mexico’s bustling capital to prescribe ivermectin to COVID-19 positive patients has resulted in a 52–76 percent reduction in hospitalizations, according to research by the Mexican Digital Agency for Public Innovation (DAPI), Mexico’s Ministry of Health, and the Mexican Social Security Institute (IMSS).

Concerned about hospital capacity in the summer of 2020, the Mexican government devised an aggressive testing regime, ramping up from 3,000 tests per day in June to around 24,000 antigen tests every day by that November, according to TrialSiteNews. Mexico City Ministry of Health head Oliva López later announced that doctors will give ivermectin and azithromycin to treat COVID-19.

“The Ministry of Health has identified that there is enough evidence to use in people positive for SARS-CoV-2, even without symptoms, some drugs such as ivermectin and azithromycin,” López confirmed in a press conference.

Local authorities created a home-treatment-kit, including ivermectin, for its 22 million-strong population on December 28, 2020, following a spike in cases of COVID-19.

Individuals testing positive for COVID from an antigen test, and who were experiencing at least mild symptoms, began receiving one of the government’s ivermectin-based treatment kits from December 29.

As part of the program of testing and early treatment, the Mexican government opened a study to track the effect that early treatment of COVID with ivermectin was having on the city’s population. Run by the Mexico Ministry of Health, DAPI, and IMSS, a phone-based monitoring program traced the health of individuals testing positive for COVID with an antigen test. The study followed two cohorts — those who received ivermectin and those who did not — and included 200,000 people, TrialSiteNews revealed.

Using the data garnered from its phone-call-based monitoring system and hospital data on admissions for COVID-19, the researchers discovered a significant reduction in hospitalizations for the group administered ivermectin versus the group which was not, totaling between 52 percent and 76 percent effective at preventing hospitalization.

Dr. Juan J. Chamie-Quintero, a senior data analyst at private Colombian university EAFIT, followed the trends in hospitalizations and deaths in Mexico City before and after the government implemented its ivermectin treatment program.

Chamie-Quintero’s findings corroborated the Mexican government’s observations. The charts below, posted to Chamie-Quintero’s Twitter page, show COVID hospitalizations and deaths both peaking around the middle of January 2021, about two weeks after ivermectin started being distributed on December 29.

COVID-19 in Mexico

Since December 29 Mexico City started using ivermectin treatment in COVID-19 positive patients. Up to Jan 22 2020 they had delivered more than 50,000 treatments.

Update (data up to Feb 6 2020 – charts up to Jan 31) pic.twitter.com/xyEfQP4XQE pic.twitter.com/T1Iy9UHjaR

— J Chamie (@jjchamie) February 7, 2021

In the month following, over 50,000 treatments had been delivered, coinciding with a steep drop in the number of both hospitalizations and deaths involving COVID-19 in Mexico City.

https://www.citizensjournal.us/covid-deaths-plunge-after-major-world-city-introduces-ivermectin/

COVID deaths plunge after major world city introduces ivermectin

Authorities create home-treatment-kit for 22 million-strong population

A citywide initiative in Mexico City to prescribe ivermectin to COVID-19 patients resulted in a plunge in hospitalizations and deaths, two studies found.

Hospitalizations were down by as much as 76%, according to research by the Mexican Digital Agency for Public Innovation, Mexico’s Ministry of Health and the Mexican Social Security Institute, according to a TrialSiteNews report highlighted by LifeSiteNews.

Earlier this month, as WND reported, a significant decrease in cases in India coincided with the national health ministry’s promotion of ivermectin and hydroxychloroquine treatments.

In Mexico City, after a spike in cases in December, the city’s Ministry of Health created a home-treatment kit for residents. The city’s metro population is 22 million.

At the time, the head of the Mexico City Ministry of Health, Oliva López, said told reporters her agency had determined “that there is enough evidence to use in people positive for SARS-CoV-2, even without symptoms, some drugs such as ivermectin and azithromycin.”

Beginning Dec. 29, people who tested positive for COVID from an antigen test and who were experiencing at least mild symptoms began receiving one of the government’s ivermectin-based treatment kits, TrialSiteNews reported.

The Mexican government then began a study to track the impact of the early treatment of COVID with ivermectin on the city’s population.

The study tracked 200,000 people, dividing in two cohorts — those who received ivermectin and those who did not.

Are governments preventing the public from getting treatments that actually help defeat COVID?

Through a phone-call-based monitoring system and hospital data on admissions for COVID-19, the researchers found a reduction of between 52% and 76% in hospitalizations for those who took ivermectin compared to those who did not.

The government’s findings were corroborated by Dr. Juan J. Chamie-Quintero, a senior data analyst at private Colombian university EAFIT.

He found that excess deaths in the city dropped sharply only a few weeks after the ivermectin treatments began.

Chamie-Quintero also conducted a study in Peru, where the government approved ivermectin as a treatment for the virus in May 2020.

In the 24 Peruvian states that adopted early use of ivermectin treatment, excess deaths plummeted on average by 59% just 30 days after the peak death rate. And it had dropped 75% after 45 days in those over 60 years old.

‘Large, statistically significant reductions in mortality’

Worldwide, more than 50 peer-reviewed studies have shown the effectiveness of ivermectin as a treatment and prophylaxis against COVID-19.

A study by the American Journal of Therapeutics that analyzed 18 randomized controlled treatment trials found ivermectin elicited “large, statistically significant reductions in mortality, time to clinical recovery, and time to viral clearance” in COVID patients.

The study concluded that “the many examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an oral agent effective in all phases of COVID-19 has been identified.”

In February, a peer-reviewed study found that invermectin reduces coronavirus infections, hospitalizations and deaths by about 75%.

Ivermectin, in more than 30 trials around the world, causes “repeated, consistent, large magnitude improvements in clinical outcomes’ at all stages of the disease,” according to the study, which was published in the U.S. journal Frontiers of Pharmacology.

The evidence is so strong, the researchers believe, the anti-parasitic drug should become a standard therapy everywhere, hastening global recovery.

“The data is overwhelming – we are in a pandemic, and this is an incredibly effective way to combat it. If we use ivermectin widely, our societies can open up,” said study co-author Professor Paul Marik, director of emergency and pulmonary care at Eastern Virginia Medical School.

A previous study by Professor Andrew Hill of Liverpool University also found ivermectin cuts death rates by about 75%.

‘Inaction in front of mounting evidence’

Dr. Pierre Kory, the chief medical officer of the Front Line Covid-19 Critical Care Alliance, is known for his congressional testimony about the effectiveness of ivermectin. In a live Zoom conference May 13, he showed the promising data from various states in India in the two weeks after ivermectin was promoted.

https://newsrescue.com/the-undeniable-ivermectin-miracle-indias-240m-populated-largest-state-uttar-pradesh-horowitz/

The Undeniable Ivermectin Miracle in India’s 240m Populated Largest State, Uttar Pradesh – Horowitz - NewsRescue.com

Uttar Pradesh might sound obscure to most Americans, but it is the most populated state in India, with urban areas that rival the most densely populated cities in the U.S. Yet, miraculously, despite housing a population of 240 million people, this northern state has been averaging only 24 cases.

Last year, the northern state of Uttar Pradesh began dispensing ivermectin liberally and encouraging people to take it early on and even preventively. As Trial Site News reported earlier this year, “By the end of 2020, Uttar Pradesh — which distributed free ivermectin for home care — had the second-lowest fatality rate in India at 0.26 per 100,000 residents in December. Only the state of Bihar, with 128 million residents, was lower, and it, too, recommends ivermectin.”Don’t miss out on content from Dave Rubin free of big tech censorship. Listen to The Rubin Report now.

As you can see, COVID has been dead in Uttar Pradesh with the exception of a very brief six-week spike in the early spring. Uttar Pradesh likely would have been the first world experiment of what a given area would have looked like had they been taking ivermectin from day one before a wave hit. Unfortunately, hundreds of thousands of seasonal migrants fled Mumbai and other big cities when the Delta wave hit and all settled back in their villages in Uttar Pradesh, giving them the same spike that every other state got because those people were not on ivermectin. As the AP reported in mid-April, during the surge in Uttar Pradesh, many of these seasonal workers who work half the year in the big cities returned home to their villages. They were likely not taking ivermectin.

But when the state began distributing the drug to everyone, cases plummeted quicker and sharper than anywhere else we’ve seen in the world, and the gains have held for months with record low cases. Dr. Surya Kant Tripathi, head of the Respiratory Medicine Department, King George Medical University, Lucknow, told the Financial Express Online in April that the state began giving ivermectin to everyone who was in home isolation (rather than telling them to do nothing until they can’t breathe, like we do here in the United States).

They also avoided use of the odious remdesivir. “All trials are saying that this drug is not effective in the treatment of COVID-19, rather it is complicating and resulting in mortality of patients,” said Dr. Tripathi. “At so many centers, remdesivir trials were stopped. Also, remdesivir is costing minimum of Rs 5,000 per vial.”

Overall, the death rate in Uttar Pradesh was roughly 95 per million people, roughly 1/20 the death rate of the U.S. More importantly, despite being the largest state in India, it incurred one-third the death rate of the country as a whole.

Take a look at this comparison between the death curve in Uttar Pradesh and the curve in India at large:

 

You will see that Uttar Pradesh experienced a plummeting of deaths more precipitous than India in the aggregate. Moreover, while cases and deaths in recent months have generally been pretty low in India because most people already got the virus, the pandemic is completely dead in Uttar Pradesh.

MSN: Uttar Pradesh government says early use of Ivermectin helped to keep positivity, deaths low

To put this comparison in another perspective, it took from May 9 to June 23 (45 days) for cases to decline 86% off the peak seven-day average for India at large. Not only did Uttar Pradesh peak earlier (April 27), it took just 30 days for it to achieve an 86% drop. By the 45-day window of comparison, cases in Uttar Pradesh had already dropped 98%. Today, it stands at 99.93% off the peak!

Now let’s compare this to the state of Kerala, which has removed ivermectin and other proven therapeutics from its treatment protocol and has gone all in on the ineffective remdesivir. Not only have cases not declined, but they have gone backward.

 

Remember, Kerala, at 34 million people, is just a fraction of the size of Uttar Pradesh.

Furthermore, just 4.5% of people in Uttar Pradesh are fully vaccinated, compared to 20% in Kerala. In this tiny state, already 70% of people 45 years and older and almost 56% of its population have had at least one shot.

Some might suggest that Kerala, being a southern state, is not a good comparison to the northern state of Uttar Pradesh because it is likely on a different epidemiological schedule. However, while Uttar Pradesh was the first state to use ivermectin, others have followed suit. Goa, which is a southern state, began offering ivermectin to all adults on May 11 and experienced a remarkable and durable decline.

 

DelhiKarnataka, and Uttarakhand also used ivermectin widely and have basically eradicated the virus.

Thus, if anything, if we are to believe a government can force people to inject medicine into their bodies to stop the virus, governments everywhere would be following the science by a factor of 100 were they to mandate ivermectin rather than the vaccines. Everyone now agrees the vaccines do not stop transmission. The only question is how long the efficacy against serious illness lasts, for whom, and whether it broadly creates antibody dependent disease enhancement.https://playlist.megaphone.fm/?e=BMDC2861655210

We already have dozens of studies vouching for the efficacy of ivermectin. While the establishment likes to complain about the sample size of each one individually, as one study published in Nature noted, “The probability that an ineffective treatment generated results as positive for the 55 studies to date is estimated to be 1 in 23 trillion (p = 0.000000000000043).” The story of Uttar Pradesh and the other Indian states that used ivermectin certainly demonstrates this.
Ivermectin was regarded as a “wonder drug” responsible for virtually eradicating river blindness in Africa. Given its robust anti-viral and anti-inflammatory mechanisms of action, Uttar Pradesh is a living testament that it could have been used to wipe COVID off the map as well. Sadly, the Western world would rather bankrupt us and cause more deaths for politically driven solutions that don’t work than cede back to the people the control they’ve established. Perhaps there is a lot we can learn from the third world, for we are now seeing the growth of a “fourth world” mentality that is much more destructive than the third world.

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